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Measles IgM - RRPL

Discipline

Microbiology

Overview

Description

  • Measles is a viral, highly contagious, airborne disease characterized by cough, coryza, conjunctivitis, fever, Koplik's spots and a characteristic erythematous rash.

  • The presence of measles-specific IgM indicates acute or recent measles infection or recent measles vaccination.

Ordering recommendations

  • Measles IgM may be ordered for patients exhibiting Measles symptoms.

  • NOTE:  IgM should only be requested on symptomatic patients.  If acute Measles infection is suspected, an NP-swab, throat swab, or urine should also be submitted for NAAT (PCR) testing (see Measles NAAT compendium entry).

Alias

  • Rubeola IgM

Specimen Information

Specimen types accepted

  • Serum

Specimen collection container

  • Serum separator tubes (SST; Tiger top or Gold top)

Collection procedure

  • Serum (SST): Collect blood in serum separator vacutainer (SST). Centrifuge. Aliquot.

Required volume

  • 1mL (minimum)

Transport and stability

  • Serum may be shipped at ambient temperature.

Performance

Methodology

  • Qualitative chemiluminescence immunoassay from DiaSorin (Positive/Indeterminate/Negative)
  • NOTE: Results should be interpreted in conjunction with clinical symptoms, exposure, and vaccination history.

Days/times performed

  • All specimens will be tested at RRPL.

Maximum laboratory time

  • Turn-around-time of 3 days from receipt in lab.

  • Positive Measles IgM results are reported to a Medical Health Officer.

  • NOTE:  Specimens positive for Measles IgM will automatically receive Measles IgG testing.

Specimen retention time

  • Specimens retained for 10 days after testing.

Last Updated: October 23, 2025